Top 6 Ingredients for Acne
According to Science & the FDA


When choosing an acne product, it’s easy to get confused with so many different ones to choose from. Fortunately, there are actually only a few ingredients that are FDA approved for acne and scientifically proven, which can help you make an informed decision.

Best FDA Approved & Scientifically Proven Ingredients:


Benzoyl peroxide
As seen in: Neutrogena On-The-Spot Acne Treatment

Countless clinical trials over the decades have shown that besides Accutane, benzoyl peroxide is the most effective acne treatment for most people. "It's the most effective over-the-counter ingredient for actually treating acne as opposed to only preventing it," says Dr. Schultz. "It kills bacteria, removes excess oil, and exfoliates dead skin cells." So why doesn’t every acne treatment just use benzoyl peroxide? The main issue is that it is very strong and is known to cause dryness, flaking, redness and irritation. This makes it difficult to use enough of it to completely get rid of acne, as most people can only handle a very small amount on their face. Also, this irritation can actually reverse the good that it does, as irritation can cause acne.


Accutane (isotretinoin)
As seen in: Prescription only

Accutane is a prescription oral treatment that gets rid of acne for about 2 out of every 3 people that take it over the course of 16-20 weeks. However, it is usually only used as a last resort and for very severe acne when all other treatments have failed as it can comes with a long list of serious potential side effects such as premature aging, joint pain, weakened night vision, liver inflammation, and is known to cause major birth defects. Accutane’s effect on mental health is also a concern as it “can cause headache, depression, fatigue, irritability, aggression, even personality change and psychosis” says Harvard health and can even lead to suicide in extreme cases. For these reasons, it must be used under strict supervision of a doctor, which includes monthly blood testing.


Salicylic acid (BHA)
As seen in: Murad Clarifying Cleanser

Salicylic acid is probably the most popular ingredient next to benzoyl peroxide for treating acne and is much more gentle on the skin. It is particularly effective for treating mild breakouts and blackheads as it works by breaking up dead skin cells and unclogging your pores of any dirt or oil. However, salicylic acid is not strong enough on its own and should be paired with other products as part of a skincare routine.


As seen in: De La Cruz Sulfur Ointment 10% Acne Medication Ointment

Sulfur is good at absorbing oil on the skin, which helps dry the skin and exfoliate dead skin cells. Unfortunately, it smells like rotten-eggs, which turns off many people from using it. It is a good choice for people who are allergic to benzoyl peroxide, as it is effective at treating acne. However, it is usually paired with other ingredients in order to help combat the smell along with other products that help treat acne as sulfur, on its own, is not the most effective treatment.



Best Natural Ingredients:
Although there aren’t too many natural ingredients that are very effective for acne, since acne is difficult to treat in general, there are two that stand out from the rest and are actually quite effective.


Tea Tree Oil
As seen in: Burt's Bees Herbal Blemish Stick

When it comes to natural, tea tree oil is by far the most effective. It’s antibacterial and anti-inflammatory properties to help calm acne. In a clinical trial, researchers found that tea tree oil worked just as well as benzoyl peroxide, but was not as fast acting and took longer to get similar results.


Alpha hydroxy acids (AHA)
As seen in: Pixi Beauty Glow Tonic

AHAs are a class of acids that can be naturally derived from fruits and exfoliate the skin. They are great at removing and loosening dead skin cells, which helps clear blocked pores. Glycolic and lactic acid are two popular AHAs and are commonly used at spas for facials and in skincare products.





How to choose a product:
When it comes to actually choosing a product, the one that’s best for you depends on your skin type along with the severity of your acne. Here are some general guidelines outlined by Mayo Clinic, which is one of the most respected and well known hospitals in the world:


Use products with different active ingredients to treat stubborn acne - Acne ingredients work in different ways, so you may find it helpful to use varying products and ingredients to treat stubborn acne.

Be patient - Treating acne with acne products takes time and patience. It may take two or three months of daily use of an acne product to see results. And acne may look worse before it gets better.


You can do this by experimenting with different products with varying active ingredients before you find what works for you, or you can use SMACNE, which is the first treatment in history to combine the very best ingredients from both science and nature together such as benzoyl peroxide, salicylic acid, tea tree oil, and alpha hydroxy acids all into a simple to use 2 step kit to create the most complete solution for all types of acne and skin types. This takes out all the guesswork out for you, since most other acne treatments contain only 1 main acne-fighting ingredient, which is why you usually have to go through several types of products before finding one that works for you. It’s like having 7 products all packed into a single solution.


Real People, Real Results

"Smacne completely cleared up my acne!" - Katy

"I've tried everything, and Smacne is the only thing that's worked" - Mark

"Smacne completely cleared up my acne!" - Katy

"I've tried everything, and Smacne is the only thing that's worked" - Mark


SMACNE also balances the ingredients so that they all work together and enhance each other’s acne-fighting ability along with minimizing any negative side effects that normally come with acne fighting ingredients such as dryness and irritation to create an effective, yet gentle treatment by using soothing and hydrating ingredients like:



Jojoba oil: This “oil” is actually a wax so it doesn’t cause breakouts and is recommended by doctors as a moisturizer for acne-prone skin, as it is very similar to the natural oil your skin produces and doesn’t clog pores.



Aloe vera 100x: Aloe vera compressed using a special process to make it 100 times more concentrated and much more potent



Hyaluronic acid: Your skin naturally makes this acid and its what helps keep your skin looking firm, young, and hydrated, as it can hold over 1,000 times its weight in water, making it one of the most water loving molecules known to man. It is a very common ingredient in high-end luxury anti-aging creams and is a favorite in clinical trials.



You can get a free trial of SMACNE's award winning and scientifically proven formula so that you can see the results for yourself. You be the judge. Just pay shipping ($7.95).


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